Biomox
(Capsules-Powder for oral suspension & Vials)
·Composition:
Each capsules contains:
Amoxycillin(as trihydrate)……………..250 mg or 500 mg.
Each 5 ml of the reconstituted suspension contains:
Amoxycillin(as trihydrate)……………..125 mg or 250 mg.
Each vial contains:
Amoxycillin(soduim)…………………...250 mg or 500 mg or 1000 mg.
Properties:
Amoxycillin is an acid resistant, semi-synthetic penicillin with a broad
spectrum of activity.
Biomox is bactericidal to a wide range of G+ and G- micro-organisms.
Amoxycillin is rapidly absorbed whether the stomach is empty or not. Its peak
blood level is 2 & 1/2 times that of the same dose of ampicillin.
The therapeutic level lasts for up to 8 hours.
Biomox is widely distributed in body tissues and fluids.
Indications:
·Respiratory tract infections:
Pneumonia,Bronchitis, Broncho-pneumonia,
Bronchiectasis,Sinusitis,Otitismedia,
Tonsilitis, Pharyngitis, Laryngitis,……….etc.
·Gastro-intestinal tract infections:
Enteritis, biliary tract infections…………………etc.
·Genito-urinary tract infections:
Cystitis, Urethritis, Gonorrhea…………………..etc.
·Skin and soft tissues infections:
Cellulitis, Erysipelas, Boils, Carbuncles………..etc.
·Contraindications:
Hypersensitivity to penicillin.
Precautions:
As with any potent drug, periodic assessment of renal, hepatic and
hematopoietic function should be made during prolonged therapy. The possibility
of super infections with mycotic or bacterial pathogens should be kept in mind
during therapy. If super infections occur, the drug should be discontinued
and/or appropriate therapy instituted.
Dosage & route of administration & duration:
·Adults:
§ Mild infections…………………….250 mg every 8 hours.
§ Moderate to severe infections……..500 mg every 8 hours.
§ Very severe infections……………..1000 mg every 8 hours.
·Children:
§ Up to 10 years..........125-250 mg every 8 hours.
§ Under 20 kg body weight............20-40 mg/kg daily in 3 divided doses
·To reconstitute the dry powder for suspension:
§ Add distilled water to the bottle to the mark and shake well after each addition.
§ The reconstituted formulation is stable for 7 days.
§ Shake well before use.
·To reconstitute the vial:
§ For I.M. injection, the powder is dissolved in 2-3 ml of water of injection.
§ For I.V. injection, the powder is dissolved in 5-10 ml of water of injection.
§ Reconstituted solutions for I.V. or I.M. should be used immediately or within 2 hours maximum
§ if kept at room temp. within 24 hours max. if kept at 5 degree.
Adverse effects:
·In rare cases diarrhea, indigestion or skin rash may occur but such cases are usually mild and transient.
Storage:
Keep at temperature not exceeding than 30ºC.
Keep out of the reach of children.
Presentation:
Box of 8,12,16,500 and 1000 capsules.
Box of one vial and 50 vials.
Bottle of powder for oral susp. 80 and 100 ml.
Produced by: sedico pharmaceutical company
Imported by: abuubakar sadiiq pharmaceutical company