 - Composition:
Each teaspoonful (5ml) contains:
Terbutaline sulfate ................. 1.5mg
Each tablet contains:
Terbutaline sulfate ................. 2.5mg
Properties:
Terbtaline sulfate is a selective beta-adrenoceptor stimulant, with selective bronchodilator action. It is more selectively acting on the B2 _receptors of the tracheal and bronchial smooth muscles but its effect is relatively weak on the B1_receptors of the heart; therefore palpitations seldom occurs.
Indications:
Bronchialasthma, chronicbronchitis,emphysemaand other broncho-pulmonary disorders involvingbronchospasm.
Contraindications:
Patients with hypertension, myocardial insufficiency, and hyperthyroidism.
Patients sensitive to sympathomimetic amines.
hypersensitivity to any of the constituents.
Sleep disturbances and behavioral effects have been observed
 - Drug interactions:
Beta blockers especially nonselective e.g. propranolol may partially or totally inhibit the effect of beta stimulants so avoid concomitant use.
Use with caution in patients receiving other sympathomimetics.
With corticosteroid: increased risk of hypokalaemia.
Diuretic increased risk of hypokalaemia.
Overdose:
Possible symptoms and signs: headache, anxiety, tremors, tonic cramp, palpitations.
arrhythmias, fall in blood pressure.
Lab. Findings: hypokalemia and hyperglycemia and lactic acidosis may occur.
Precautions:
Care should be taken in patients with previous history of peptic ulcer.
Care should be taken in patients suffering from myocardial in sufficiency or thyrotoxicosis and in diabetic patients.
The drug is only used during pregnancy if clearly needed.
Terbutaline sulfate excreted into breast milk but effect on the infant is unlikely at therapeutic
Dosage & route of administration & duration:
Adults:2 tablets 2-3 times daily.
Children:0.075-0.29 mg/ kg body weight 3 times daily as follow:
| Kg (Wt.) |
Dosage |
| 14 |
3.5 ml x 3 |
| 16 |
4 ml x 3 |
| 18 |
4.5 ml x 3 |
| 20 |
5 ml x 3 |
| 24 |
6 ml x 3 |
| 28 |
7 ml x 3 |
| 32 |
8 ml x 3 |
| 36 |
9 ml x 3 |
| 40 |
10 ml x 3 |
Adverse effects:
In unusually sensitive patients, tremor, headache, tachycardia, palpitation, dizziness may occur. These effects usually disappear within the first week.
Potentially serious hypokalemia may be observed. Sleep disturbances and behavioral effects have been observed in children.
Storage:
Keep at temp. not exceeding 30°C.
Keep medicine out of reach of children.
Presentation:
Syrup: Bottle of 120 ml.
Tablets: Box of 20 tablets.
Box of 1000 tablet
DISTRIBUTOR: Abuubakarsadiiq Pharmaceutical co
MANUFACTRED BY: SEDICO |
