PEPZOL 40 mg – High-Strength Omeprazole for Acid-Related Disorders

PEPZOL 40 mg, manufactured by Hikma, contains Omeprazole 40 mg, a high-strength proton pump inhibitor (PPI) used to treat severe or persistent acid-related conditions.

This dose is ideal for patients requiring stronger and longer-lasting gastric acid suppression compared to the 20 mg formulation.

Composition:

Each capsule contains Omeprazole 40 mg

Key Benefits

• Strong gastric acid suppression
• Relieves severe GERD symptoms
• Supports healing of esophageal damage
• Treats gastric & duodenal ulcers
• Supports H. pylori eradication therapy
• Reduces inflammation in gastritis
• Once-daily convenient dosing

How PEPZOL 40 mg Works

Omeprazole 40 mg

• Blocks the final step of acid production in parietal cells
• Inhibits the H⁺/K⁺ ATPase proton pump
• Reduces both daytime & nighttime acid secretion
• Promotes healing of the stomach & esophagus

Result:
✔ Stronger symptom relief
✔ Faster ulcer healing
✔ Reduced irritation & inflammation
✔ Improved quality of life in GERD patients

Indications

PEPZOL 40 mg is commonly used for:

1. Severe GERD (Gastroesophageal Reflux Disease)

• Persistent heartburn
• Acid regurgitation
• Throat burning
• Chronic cough related to reflux

2. Erosive Esophagitis

• Esophageal irritation from prolonged acidity
• Requires high-strength PPI therapy

3. Peptic Ulcers

• Gastric ulcers
• Duodenal ulcers

4. Part of Triple Therapy for H. pylori Infection

(when used with antibiotics as prescribed)

5. Gastritis & Hyper-Acidity Conditions
6. Zollinger-Ellison Syndrome

(physician-directed high-dose therapy)

Dosage & Administration

• Adults: 1 capsule (40 mg) once daily
• Take 30–60 minutes before a meal
• Swallow whole with water
• Do not crush or chew
• Treatment length varies according to condition
• For H. pylori therapy: taken twice daily with antibiotics (as prescribed)

Safety & Side Effects

Omeprazole is generally well tolerated. Mild side effects include:

• Headache
• Abdominal discomfort
• Nausea or diarrhea
• Gas or bloating
• Dizziness

Seek medical attention for:

• Persistent diarrhea
• Allergic reaction
• Vitamin B12 deficiency symptoms with long-term use
• Low magnesium (rare)

Who Should Use PEPZOL 40 mg?

• Adults with severe GERD
• Patients with erosive esophagitis
• Individuals with persistent ulcer symptoms
• Anyone needing strong PPI therapy as directed by their doctor

Disclaimer: This information is for educational purposes only and does not replace medical advice. Use as directed by a healthcare professional.